The endometrial microbiome refers to the community of micro-organisms (also calld an ecosystem), which includes bacteria, that reside in the endometrium, the lining of the uterus. This microbiome plays a significant role in reproductive health and pregnancy outcomes.
Key Points about the Endometrial Microbiome
Composition:The endometrial microbiome is typically dominated by beneficial bacteria such as, Lactobacillus species which help mantain a healthy environment.
Role in pregnancy: A balanced endometrial microbiome is crucial for successful embryo implantation and maintenance. It interacts with the immune system to support a conducive environment for the immune system.
Impact on Pregnancy
Dysbiosis: An imbalance of the endometrial microbiome that can lead to adverse pregnancy outcomes. This includes increased risk of miscarriage, preterm birth and implantation failure.
Inflammation: Dysbiosis can trigger inflammotory responses in your endometrium disrupting the delicate balance needed for embryo implantation and growth.
Infertility: Studies have shown that certain bacterial profiles in the endometrium are associated with lower success rates in assisted reproductive technologies like IVF.
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